As soon as you accept it

There are many things that will drastically change during your lifetime. No matter if you like it or not you have to adapt to the changes. Sure you can be frustrated or even angry about it but it won't get you anywhere. The sooner you accept it the sooner you will get over it so you can move on. Accepting it doesn't mean you like the change. It means you realize that whether you like it or not you have the wisdom to know you have to accept the things you can not change.